Designing non-peptide peptidomimetics in the 21st century: inhibitors targeting conformational ensembles

J Med Chem. 2002 Jan 31;45(3):541-58. doi: 10.1021/jm010425b.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Aspartic Acid Endopeptidases / chemistry
  • Binding Sites
  • Drug Design
  • Enzyme Inhibitors / chemistry*
  • Ligands
  • Models, Molecular
  • Molecular Mimicry
  • Peptides / chemistry*
  • Protease Inhibitors / chemistry
  • Protein Binding
  • Protein Conformation
  • Structure-Activity Relationship

Substances

  • Enzyme Inhibitors
  • Ligands
  • Peptides
  • Protease Inhibitors
  • Aspartic Acid Endopeptidases